MOTS-C

MOTS-c is a mitochondria-derived peptide studied for its role in cellular energy regulation, metabolic signaling, and responses to exercise. DeSoto Peptides supplies MOTS-C as a lyophilized research material for laboratory research.

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10/20MG PER VIAL

Lyophilized research material

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RESEARCH GRADE

Lot-specific documentation available

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BATCH VERIFIED

For laboratory research only

A MITOCHONDRIAL SIGNAL. A CELLULAR RESPONSE.

EXPLORING HOW CELLS
REGULATE ENERGY

MOTS-c is a short peptide encoded within mitochondrial DNA. Laboratory and animal studies have examined its role in AMPK signaling, a system that helps cells regulate energy use, and its effects on how cells respond to metabolic stress. These findings have not established the safety or effectiveness of MOTS-c treatment in humans.

Molecular structure with the text 'MOTS-C' above it on a black background.

Mitochondria-derived peptide
Metabolic communication

Graphic of molecular structures with the text "AMPK Signaling" above.

Cellular energy sensing
Regulation of fuel use

Digital illustration of a human cell with mitochondria, nucleus, and other organelles, with the text 'Cellular Response' above.

Metabolic stress adaptation
Changes in gene activity

WHAT THE RESEARCH SHOWS

Research has explored MOTS-c’s role in muscle metabolism, cellular stress responses, and physical performance.

A 2021 study found improved treadmill performance in treated mice and increased naturally occurring MOTS-c after exercise in humans.

Neon-style display of scientific research findings on MOTS-c's effects on treadmill performance in mice, with a note on the lack of benefits in humans, citing a 2021 study by Reynolds et al.
Neon sign displaying '10 Participants' in large blue text, with additional details about a human exercise study on healthy young men and the measurement of naturally occurring MOTS-c, noting no MOTS-c was administered.
Neon sign that says 'Nature Communications' with a subtitle 'Peer-reviewed research' on a black background.
Neon sign with blue border, black background, and text stating '4 HOURS POST-EXERCISE FOLLOW-UP Circulating MOTS-c returned to baseline after resting No MOTS-c administered.'
Neon-lit academic journal article title and citation regarding a study on Achilles tendon healing in rats.
Neon-lit academic journal article title and citation regarding a study on Achilles tendon healing in rats.

MOTS-C 10/20MG

Research material with batch-specific documentation.

Learn More About Mots-C
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For research use only. Not for human consumption